Social And Financial Impact Of Dravet Syndrome

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Cognitive and social impairment in mouse models mirrors dravet syndrome.

Commentary Dravet syndrome is an infant-onset epileptic encephalopathy characterized by generalized clonic, tonic–clonic, or hemi-clonic seizures. Patients subsequently develop other types of seizures, including myoclonic, absence, or partial seizures. Seizures are often refractory to conventional antiepileptic drugs and lack ofadequate seizure control is correlated with poor outcomes. Developm...

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Dravet syndrome

"Dravet syndrome" (DS) previously named severe myoclonic epilepsy of infancy (SMEI), or epilepsy with polymorphic seizures, is a rare disorder characterized by an early, severe, generalized, epileptic encephalopathy.DS is characterized by febrile and afebrile seizures beginning in the 1st year of life followed by different types of seizures (either focal or generalized), which are typically res...

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Vaccinations and Dravet Syndrome.

Investigators from various university hospitals, reference medical institutions and epilepsy centers, and the national institute for public health and environment in the Netherlands, studied the effect of vaccinations on seizure risk and disease course in patients with Dravet syndrome (DS).

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Dravet Syndrome

Dravet syndrome (DS) is one of the refractory epileptic encephalopathies [3], one of the spectra of severe myoclonic Epilepsy of Infancy (SMEI) which occurs in otherwise healthy individuals [2]. Its incidence has been estimated to be 1 in 2000040000. It is more common in males than in females. Positive family history is encountered in one fourth of the cases. DS Usually started by clonic/tonic-...

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Phenotypes of Dravet Syndrome

Researchers from the University of Washington in Seattle studied selective heterozygous and homozygous deletions of the voltage gated sodium channel (Nav1.1) in parvalbumin (PV) or somato-statin (SST) expressing interneurons.

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ژورنال

عنوان ژورنال: Value in Health

سال: 2017

ISSN: 1098-3015

DOI: 10.1016/j.jval.2017.08.640